Top B12 supplements for energy and overall wellness

How to choose the right B12 supplement

Vitamin B12 is one of the most important nutrients for good health, yet the human body cannot make it on its own. Ideally, people would get all they need from a balanced diet, but that is not always easy in practice.

If you think you may not be getting enough B12, a supplement can be a practical option. These products come in a wide range of forms and strengths, making it easier to find one that fits your needs. One standout choice is New Chapter Fermented Vitamin B Complex, an organic formula made for quick absorption.

Who may need a B12 supplement?

Anyone showing signs of B12 deficiency may want to consider supplementation. Possible symptoms include depression, irritability, yellowing skin, mouth ulcers, a pins-and-needles feeling in the hands or feet, blurred vision, dizziness, muscle weakness and similar issues.

Even without obvious symptoms, some people are more likely to develop low B12 levels and may choose to take it preventively.

• Vegans: Animal foods are the main dietary source of B12, so vegans are especially vulnerable to deficiency.
• People with digestive issues: Those with Crohn’s disease, pernicious anemia or celiac disease may have trouble absorbing enough B12 from food.
• Adults over 50: As people age, hydrochloric acid levels often decline, which can make it harder for the body to break down and absorb B12 from food.

Potential benefits of B12 supplements

B12 supplements may offer a wide range of benefits, including the following:

• Supports bone health and may help prevent osteoporosis.
• May lower the risk of macular degeneration.
• Plays a role in helping prevent serious birth defects.
• Helps with red blood cell production.
• May improve mood and boost energy.
• May reduce the risk of heart disease.
• Supports healthy skin, nails and hair.

What to consider before buying B12

Common B12 types

Supplements usually contain one of four forms of B12.

• Methylcobalamin is a naturally occurring form and the most active in the body, so it is often used in premium supplements.
• Cyanocobalamin is a synthetic, more stable and less expensive form that is commonly found in budget products. Studies differ on whether it is easier or harder for the body to absorb than methylcobalamin.
• Adenosylcobalamin is less stable than the other forms but can come from algae, which makes it suitable for vegans.

Supplement formats

Oral B12 supplements are sold as tablets, chews, lozenges and sprays. Some experts advise against tablets because they take longer to break down and reach the bloodstream. Still, there is no clear evidence that one regular oral form works better than another, so personal preference matters most.

If pills are not your thing, B12 is also available as transdermal creams and patches, along with nasal sprays and gels. These options have been shown to work as well as oral supplements. The best choice is usually the one you will use consistently.

Typical cost of B12 supplements

Prices vary depending on the type and format. Most good-quality gummies, tablets and sublingual melts cost between $10 and $20. Creams, patches and liquid drops are generally a little more expensive, usually ranging from $20 to $30.

B12 supplement FAQ

Does everyone need a B12 supplement?

A. People who eat a balanced diet and absorb B12 normally from food do not usually need supplements. Those with a deficiency or those in higher-risk groups should ask a doctor whether supplementation is a good idea.

Are there side effects from B12 supplements?

A. Oral and topical B12 supplements are generally considered safe for most people and rarely cause side effects when used as directed. People receiving high-dose injections may experience headaches, nausea, vomiting, diarrhea, weakness, fatigue and tingling in the hands and feet.

Do B12 supplements interact with other medications?

A. Some medications can affect the body’s ability to absorb B12, including Prilosec and Prevacid. Check with your doctor before starting any new supplement to make sure it is safe to use alongside your medications.

Best B12 supplement picks

Top overall B12 supplement

What you need to know: This vegetarian-friendly, kosher-certified supplement combines methylcobalamin and cyanocobalamin for strong absorption.

What you’ll love: It includes herbs meant to support absorption and help increase energy.

What you should consider: The dosage is relatively low.

Best value B12 supplement

What you need to know: These high-potency lozenges have a cherry flavor and can be chewed or allowed to dissolve.

What you’ll love: They are vegan-friendly and gluten-free.

What you should consider: The strength may be too high for people without a deficiency.

Another option worth a look

What you need to know: This B12 spray is easy to absorb and includes a blend of superfoods, making it a good pick for anyone who dislikes swallowing tablets.

What you’ll love: It contains no synthetic ingredients or genetically modified organisms.

What you should consider: It may lose freshness if it is not stored correctly.